E24D (p.Glu24Asp) variant of BCR (P11274)
E24D (p.Glu24Asp) in BCR (P11274) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
E24D (p.Glu24Asp) variant details
- p.Glu24Asp
- NCI-TCGA Cosmic COSV5993
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.06
- CADD 15.40
- PolyPhen-2 0.02
- SIFT 0.22
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available