E19D (p.Glu19Asp) variant of BCR (P11274)
E19D (p.Glu19Asp) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
E19D (p.Glu19Asp) variant details
- p.Glu19Asp
- gnomAD 22-23181017-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.07
- CADD 17.50
- PolyPhen-2 0.02
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available