E19A (p.Glu19Ala) variant of BCR (P11274)
E19A (p.Glu19Ala) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
E19A (p.Glu19Ala) variant details
- p.Glu19Ala
- TOPMed rs1235158409
- gnomAD rs1235158409
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.19
- CADD 24.40
- PolyPhen-2 0.55
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available