A10S (p.Ala10Ser) variant of BCR (P11274)
A10S (p.Ala10Ser) in BCR (P11274) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
A10S (p.Ala10Ser) variant details
- p.Ala10Ser
- gnomAD 22-23180988-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.20
- CADD 24.90
- PolyPhen-2 0.99
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available