V84L (p.Val84Leu) variant of BCOR (BCL-6 corepressor)
V84L (p.Val84Leu) in BCOR (BCL-6 corepressor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
V84L (p.Val84Leu) variant details
- p.Val84Leu
- ExAC rs747983005
- TOPMed rs747983005
- gnomAD rs747983005
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.17
- CADD 21.70
- PolyPhen-2 0.99
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 7.6e-05)
- Structural context available