R46S (p.Arg46Ser) variant of BCOR (BCL-6 corepressor)
R46S (p.Arg46Ser) in BCOR (BCL-6 corepressor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
R46S (p.Arg46Ser) variant details
- p.Arg46Ser
- TOPMed rs1935813191
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.24
- CADD 24.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available