M22I (p.Met22Ile) variant of BCOR (BCL-6 corepressor)
M22I (p.Met22Ile) in BCOR (BCL-6 corepressor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
M22I (p.Met22Ile) variant details
- p.Met22Ile
- TOPMed rs947946150
- gnomAD rs947946150
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.18
- CADD 22.80
- PolyPhen-2 0.11
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available