D37E (p.Asp37Glu) variant of BCOR (BCL-6 corepressor)
D37E (p.Asp37Glu) in BCOR (BCL-6 corepressor) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
D37E (p.Asp37Glu) variant details
- p.Asp37Glu
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0967
- REVEL 0.08
- CADD 8.56
- PolyPhen-2 0.03
- SIFT 0.28
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available