S6L (p.Ser6Leu) variant of BCL2L2 (Bcl-2-like protein 2)
S6L (p.Ser6Leu) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S6L (p.Ser6Leu) variant details
- p.Ser6Leu
- cosmic curated COSV10605
- TOPMed rs1414276111
- gnomAD rs1414276111
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.13
- CADD 23.40
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available