R59C (p.Arg59Cys) variant of BCL2L2 (Bcl-2-like protein 2)
R59C (p.Arg59Cys) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
R59C (p.Arg59Cys) variant details
- p.Arg59Cys
- cosmic curated COSV51636
- ESP rs377103042
- ExAC rs377103042
- TOPMed rs377103042
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.11
- CADD 23.50
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available