R58W (p.Arg58Trp) variant of BCL2L2 (Bcl-2-like protein 2)
R58W (p.Arg58Trp) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R58W (p.Arg58Trp) variant details
- p.Arg58Trp
- ExAC rs772303364
- TOPMed rs772303364
- gnomAD rs772303364
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.26
- CADD 25.00
- PolyPhen-2 0.98
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available