R23S (p.Arg23Ser) variant of BCL2L2 (Bcl-2-like protein 2)
R23S (p.Arg23Ser) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R23S (p.Arg23Ser) variant details
- p.Arg23Ser
- ExAC rs759748132
- TOPMed rs759748132
- gnomAD rs759748132
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.22
- CADD 21.30
- PolyPhen-2 0.04
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available