R11W (p.Arg11Trp) variant of BCL2L2 (Bcl-2-like protein 2)
R11W (p.Arg11Trp) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R11W (p.Arg11Trp) variant details
- p.Arg11Trp
- ExAC rs748717252
- gnomAD rs748717252
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.16
- CADD 25.20
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available