R11L (p.Arg11Leu) variant of BCL2L2 (Bcl-2-like protein 2)
R11L (p.Arg11Leu) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
R11L (p.Arg11Leu) variant details
- p.Arg11Leu
- ExAC rs750337260
- TOPMed rs750337260
- gnomAD rs750337260
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.22
- CADD 24.40
- PolyPhen-2 0.08
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available