M46T (p.Met46Thr) variant of BCL2L2 (Bcl-2-like protein 2)
M46T (p.Met46Thr) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
M46T (p.Met46Thr) variant details
- p.Met46Thr
- cosmic curated COSV51635
- gnomAD rs1887344145
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- REVEL 0.26
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available