K25T (p.Lys25Thr) variant of BCL2L2 (Bcl-2-like protein 2)
K25T (p.Lys25Thr) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K25T (p.Lys25Thr) variant details
- p.Lys25Thr
- ExAC rs768478219
- TOPMed rs768478219
- gnomAD rs768478219
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.11
- CADD 25.80
- PolyPhen-2 0.68
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00012)
- Structural context available