K21E (p.Lys21Glu) variant of BCL2L2 (Bcl-2-like protein 2)
K21E (p.Lys21Glu) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
K21E (p.Lys21Glu) variant details
- p.Lys21Glu
- ExAC rs770982097
- gnomAD rs770982097
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.12
- CADD 26.90
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available