G36C (p.Gly36Cys) variant of BCL2L2 (Bcl-2-like protein 2)
G36C (p.Gly36Cys) in BCL2L2 (Bcl-2-like protein 2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
G36C (p.Gly36Cys) variant details
- p.Gly36Cys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.13
- CADD 26.60
- PolyPhen-2 0.84
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available