G34R (p.Gly34Arg) variant of BCL2L2 (Bcl-2-like protein 2)
G34R (p.Gly34Arg) in BCL2L2 (Bcl-2-like protein 2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G34R (p.Gly34Arg) variant details
- p.Gly34Arg
- rs773144952
- ExAC rs773144952
- TOPMed rs773144952
- gnomAD rs773144952
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.04
- CADD 23.50
- PolyPhen-2 0.28
- SIFT 0.06
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available