F53L (p.Phe53Leu) variant of BCL2L2 (Bcl-2-like protein 2)
F53L (p.Phe53Leu) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
F53L (p.Phe53Leu) variant details
- p.Phe53Leu
- 1000Genomes rs558357593
- ExAC rs558357593
- TOPMed rs558357593
- gnomAD rs558357593
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.11
- CADD 15.80
- PolyPhen-2 0.13
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available