D63V (p.Asp63Val) variant of BCL2L2 (Bcl-2-like protein 2)
D63V (p.Asp63Val) in BCL2L2 (Bcl-2-like protein 2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
D63V (p.Asp63Val) variant details
- p.Asp63Val
- rs1270964845
- TOPMed rs1270964845
- gnomAD rs1270964845
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.495
- REVEL 0.38
- CADD 28.40
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available