A66S (p.Ala66Ser) variant of BCL2L2 (Bcl-2-like protein 2)
A66S (p.Ala66Ser) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A66S (p.Ala66Ser) variant details
- p.Ala66Ser
- 1000Genomes rs544188628
- ExAC rs544188628
- TOPMed rs544188628
- gnomAD rs544188628
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.05
- CADD 17.90
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the 1KG:LWK population (allele frequency 0.0058)
- Structural context available