A2V (p.Ala2Val) variant of BCL2L2 (Bcl-2-like protein 2)
A2V (p.Ala2Val) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
A2V (p.Ala2Val) variant details
- p.Ala2Val
- TOPMed rs1887328939
- gnomAD rs1887328939
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.22
- CADD 26.10
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 6.6e-05)
- Structural context available