A12T (p.Ala12Thr) variant of BCL2L2 (Bcl-2-like protein 2)
A12T (p.Ala12Thr) in BCL2L2 (Bcl-2-like protein 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
A12T (p.Ala12Thr) variant details
- p.Ala12Thr
- ExAC rs778308004
- TOPMed rs778308004
- gnomAD rs778308004
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.07
- CADD 23.20
- PolyPhen-2 0.16
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available