T34S (p.Thr34Ser) variant of BCL2L11 (Bcl-2-like protein 11)
T34S (p.Thr34Ser) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
T34S (p.Thr34Ser) variant details
- p.Thr34Ser
- gnomAD 2-111123845-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.06
- MetaLR 0.16
- MetaSVM -0.76
- CADD 20.40
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available
- Literature evidence available