T34I (p.Thr34Ile) variant of BCL2L11 (Bcl-2-like protein 11)
T34I (p.Thr34Ile) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
T34I (p.Thr34Ile) variant details
- p.Thr34Ile
- gnomAD 2-111123846-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.05
- MetaLR 0.19
- MetaSVM -0.81
- CADD 22.40
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 2.7e-05)
- Structural context available
- Literature evidence available