S6Y (p.Ser6Tyr) variant of BCL2L11 (Bcl-2-like protein 11)
S6Y (p.Ser6Tyr) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
S6Y (p.Ser6Tyr) variant details
- p.Ser6Tyr
- TOPMed rs1219836031
- gnomAD rs1219836031
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.33
- MetaLR 0.26
- MetaSVM -0.51
- CADD 26.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available