S35F (p.Ser35Phe) variant of BCL2L11 (Bcl-2-like protein 11)
S35F (p.Ser35Phe) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
S35F (p.Ser35Phe) variant details
- p.Ser35Phe
- gnomAD 2-111123849-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.31
- MetaLR 0.26
- MetaSVM -0.58
- CADD 27.00
- PolyPhen-2 0.99
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available