S35C (p.Ser35Cys) variant of BCL2L11 (Bcl-2-like protein 11)
S35C (p.Ser35Cys) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
S35C (p.Ser35Cys) variant details
- p.Ser35Cys
- gnomAD rs979302636
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.27
- MetaLR 0.25
- MetaSVM -0.70
- CADD 26.50
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available