R24S (p.Arg24Ser) variant of BCL2L11 (Bcl-2-like protein 11)
R24S (p.Arg24Ser) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
R24S (p.Arg24Ser) variant details
- p.Arg24Ser
- gnomAD 2-111123817-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.21
- MetaLR 0.17
- MetaSVM -0.82
- CADD 23.00
- PolyPhen-2 0.33
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available
- Literature evidence available