R24G (p.Arg24Gly) variant of BCL2L11 (Bcl-2-like protein 11)
R24G (p.Arg24Gly) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
R24G (p.Arg24Gly) variant details
- p.Arg24Gly
- gnomAD 2-111123815-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.16
- MetaLR 0.16
- MetaSVM -0.85
- CADD 22.60
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the REMAINING population (allele frequency 3.6e-05)
- Structural context available
- Literature evidence available