Q27R (p.Gln27Arg) variant of BCL2L11 (Bcl-2-like protein 11)
Q27R (p.Gln27Arg) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
Q27R (p.Gln27Arg) variant details
- p.Gln27Arg
- gnomAD 2-111123825-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.20
- MetaLR 0.16
- MetaSVM -0.68
- CADD 25.30
- PolyPhen-2 0.76
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available