Q20E (p.Gln20Glu) variant of BCL2L11 (Bcl-2-like protein 11)
Q20E (p.Gln20Glu) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
Q20E (p.Gln20Glu) variant details
- p.Gln20Glu
- gnomAD 2-111123803-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.07
- MetaLR 0.16
- MetaSVM -0.67
- CADD 18.50
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 9.6e-07)
- Structural context available
- Literature evidence available