P40L (p.Pro40Leu) variant of BCL2L11 (Bcl-2-like protein 11)
P40L (p.Pro40Leu) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
P40L (p.Pro40Leu) variant details
- p.Pro40Leu
- Ensembl rs2071836166
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.02
- CADD 14.60
- PolyPhen-2 0.02
- SIFT 0.60
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available