P33R (p.Pro33Arg) variant of BCL2L11 (Bcl-2-like protein 11)
P33R (p.Pro33Arg) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
P33R (p.Pro33Arg) variant details
- p.Pro33Arg
- ESP rs370683853
- ExAC rs370683853
- TOPMed rs370683853
- gnomAD rs370683853
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.28
- MetaLR 0.27
- MetaSVM -0.52
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.21
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available