P33L (p.Pro33Leu) variant of BCL2L11 (Bcl-2-like protein 11)
P33L (p.Pro33Leu) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
P33L (p.Pro33Leu) variant details
- p.Pro33Leu
- ESP rs370683853
- ExAC rs370683853
- TOPMed rs370683853
- gnomAD rs370683853
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.35
- MetaLR 0.26
- MetaSVM -0.54
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.26
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available