P26H (p.Pro26His) variant of BCL2L11 (Bcl-2-like protein 11)
P26H (p.Pro26His) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P26H (p.Pro26His) variant details
- p.Pro26His
- TOPMed rs375839187
- gnomAD rs375839187
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.08
- MetaLR 0.09
- MetaSVM -1.02
- CADD 22.70
- PolyPhen-2 0.46
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 0.00016)
- Structural context available