P25T (p.Pro25Thr) variant of BCL2L11 (Bcl-2-like protein 11)
P25T (p.Pro25Thr) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
P25T (p.Pro25Thr) variant details
- p.Pro25Thr
- gnomAD 2-111123818-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.35
- MetaLR 0.26
- MetaSVM -0.50
- CADD 24.90
- PolyPhen-2 0.95
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available