P25S (p.Pro25Ser) variant of BCL2L11 (Bcl-2-like protein 11)
P25S (p.Pro25Ser) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
P25S (p.Pro25Ser) variant details
- p.Pro25Ser
- gnomAD 2-111123818-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.24
- MetaLR 0.26
- MetaSVM -0.51
- CADD 25.40
- PolyPhen-2 0.93
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available