P25R (p.Pro25Arg) variant of BCL2L11 (Bcl-2-like protein 11)
P25R (p.Pro25Arg) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P25R (p.Pro25Arg) variant details
- p.Pro25Arg
- Ensembl rs1327265816
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- REVEL 0.21
- MetaLR 0.20
- MetaSVM -0.54
- CADD 25.50
- PolyPhen-2 0.95
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available