P21T (p.Pro21Thr) variant of BCL2L11 (Bcl-2-like protein 11)
P21T (p.Pro21Thr) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
P21T (p.Pro21Thr) variant details
- p.Pro21Thr
- gnomAD 2-111123806-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.15
- MetaLR 0.20
- MetaSVM -0.70
- CADD 24.40
- PolyPhen-2 0.81
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 2e-05)
- Structural context available
- Literature evidence available