P21S (p.Pro21Ser) variant of BCL2L11 (Bcl-2-like protein 11)
P21S (p.Pro21Ser) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P21S (p.Pro21Ser) variant details
- p.Pro21Ser
- ExAC rs764939886
- gnomAD rs764939886
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.18
- MetaLR 0.17
- MetaSVM -0.83
- CADD 21.60
- PolyPhen-2 0.25
- SIFT 0.36
- Most common in the South Asian population (allele frequency 1.5e-05)
- Structural context available