P21A (p.Pro21Ala) variant of BCL2L11 (Bcl-2-like protein 11)
P21A (p.Pro21Ala) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
P21A (p.Pro21Ala) variant details
- p.Pro21Ala
- gnomAD 2-111123806-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.18
- MetaLR 0.19
- MetaSVM -0.68
- CADD 23.00
- PolyPhen-2 0.58
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available
- Literature evidence available