L36V (p.Leu36Val) variant of BCL2L11 (Bcl-2-like protein 11)
L36V (p.Leu36Val) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L36V (p.Leu36Val) variant details
- p.Leu36Val
- ExAC rs749538495
- TOPMed rs749538495
- gnomAD rs749538495
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.06
- CADD 17.80
- PolyPhen-2 0.01
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available