L28F (p.Leu28Phe) variant of BCL2L11 (Bcl-2-like protein 11)
L28F (p.Leu28Phe) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
L28F (p.Leu28Phe) variant details
- p.Leu28Phe
- ExAC rs766299103
- TOPMed rs766299103
- gnomAD rs766299103
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.27
- MetaLR 0.26
- MetaSVM -0.52
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.16
- Most common in the REMAINING population (allele frequency 5.2e-05)
- Structural context available