K3R (p.Lys3Arg) variant of BCL2L11 (Bcl-2-like protein 11)
K3R (p.Lys3Arg) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
K3R (p.Lys3Arg) variant details
- p.Lys3Arg
- TOPMed rs2071806023
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.23
- MetaLR 0.25
- MetaSVM -0.54
- CADD 27.00
- PolyPhen-2 0.96
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 3e-06)
- Structural context available