K3E (p.Lys3Glu) variant of BCL2L11 (Bcl-2-like protein 11)
K3E (p.Lys3Glu) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
K3E (p.Lys3Glu) variant details
- p.Lys3Glu
- gnomAD rs2071805543
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- REVEL 0.65
- MetaLR 0.25
- MetaSVM -0.55
- CADD 28.90
- PolyPhen-2 0.96
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available