G16S (p.Gly16Ser) variant of BCL2L11 (Bcl-2-like protein 11)
G16S (p.Gly16Ser) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G16S (p.Gly16Ser) variant details
- p.Gly16Ser
- Ensembl rs1014619723
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.40
- MetaLR 0.27
- MetaSVM -0.52
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 4.1e-05)
- Structural context available