E23G (p.Glu23Gly) variant of BCL2L11 (Bcl-2-like protein 11)
E23G (p.Glu23Gly) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
E23G (p.Glu23Gly) variant details
- p.Glu23Gly
- Ensembl rs1286273190
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.15
- MetaLR 0.13
- MetaSVM -0.82
- CADD 24.80
- PolyPhen-2 0.13
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.5e-07)
- Structural context available