E15Q (p.Glu15Gln) variant of BCL2L11 (Bcl-2-like protein 11)
E15Q (p.Glu15Gln) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
E15Q (p.Glu15Gln) variant details
- p.Glu15Gln
- ExAC rs776207874
- TOPMed rs776207874
- gnomAD rs776207874
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.22
- MetaLR 0.26
- MetaSVM -0.51
- CADD 26.80
- PolyPhen-2 0.92
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available